IgA Nephropathy

About the Disease
Iga Glomerulonephritis, also known as iga nephropathy, is related to tonsillitis and glomerulonephritis. An important gene associated with Iga Glomerulonephritis is IGAN1 (IgA Nephropathy), and among its related pathways/superpathways are CCL18 signaling pathway and Mesenchymal Stem Cells and Lineage-specific Markers. The drugs Benzocaine and Tannic acid have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and heart, and related phenotypes are renal/urinary system and homeostasis/metabolism

Common Targets
VTRNA2-1 | LINC02580 | LOC105379385 | LRRC7 | AGT | DUSP3 | NRIP1 | GPR84-AS1 | FAM107B | HORMAD2 | CDH20 | AKR1C1 | G4233 | CFD | SRGAP1 | COL4A5 | LOC101928923 | AEBP2 | ICAM1 | ITGA2 | G3569 | G3479 | SUMF1 | LOC101928948 | TNFSF13 | ITGAX | NOS3 | HMOX2 | NWD2 | H1-8 | IL10RA | CCR2 | M6PR | NPHS2 | FCRLA | IL10 | IL1B | SYK | MLN | PADI6 | G3605 | WWOX | ENAH | Tyrosine Kinase (nonspecified subtype) | CNTNAP5 | HDAC7 | CFHR1 | ST6GAL1 | SGO1-AS1 | LOC105373623 | G7124 | ERG | TNFSF13B | FLT3 | CARD9 | CD38 | TNFSF12-TNFSF13 | FPGT-TNNI3K | COL9A1 | CTLA4 | IQGAP1 | LOC101927998 | MASP2 | CNTLN | CYP24A1 | TNNI3K | CFHR5 | MIR100HG | TMPRSS2 | IQSEC1 | LOC105375825 | EEF1DP3 | TLR9 | GS1-24F4.2 | AGTR1 | FCRL3 | IFNG | SETMAR | NF-kappaB (NFkB) | C1GALT1C1 | MPHOSPH6 | BACH2 | WSCD1 | GLCCI1 | RANBP9 | IL1R1 | DDR1 | LOC102724684 | BACH1 | Heme Oxygenase (HO) (nonspecified subtype) | SMARCD1 | MTMR3 | LOC105378072 | RBFOX3 | MBL2 | GPC5 | CREB3L1 | SGO1 | MIR146A | CHUK | Complement Complex | SH3RF1 | TRIM27 | LYN | NTN1 | ACOXL | SPRY2 | FCGR2A | LOC105374428 | SOX13 | TTC7A | DEFA4 | C3 | HAPSTR1 | LOC105374522 | CYP19A1 | TGFB1 | LOC105374523 | PTDSS1 | ELF1 | FCRLB | MICB-DT | PSAT1 | CFH | G596 | NOL7 | IL16 | ACCS | TNFRSF17 | C5AR1 | CCL2 | KL | LOC105372047 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | APOL1 | RNASET2 | MPDU1 | IL12A-AS1 | SIRT5 | ACYP2 | TNFSF15 | PLA2R1 | CYP11B2 | LINC01788 | MTR | HMOX1 | COL4A3 | MIR196A2 | SETX | SERPINB7 | C1GALT1 | PSMB8 | SPATS2L | DEFA6 | IL18 | IL23R | FBXO32 | B3GALT5 | HNF1B | SGIP1 | LYPD1 | VPS50 | HCAR2 | LRRC4C | UBE3D | CX3CR1 | CAMK2N1 | IL1R2 | ABCC3 | TLCD4 | EDNRA | G4780 | GPD1L | COL4A4 | LOC105376823 | TLR1 | EEA1 | HLA-DPB2 | IL22RA1 | LINC02141 | Immunoglobulin A | GAS6 | DENND1A | SOX15 | PPARG | VAV3 | CASC15 | SCN10A | G1956 | CHI3L2 | CFB | TOP1 | ASGR1 | ABCA13 | CD40LG | LOC105372802 | C5 | FCGR2B | Asialoglycoprotein Receptor (ASGPR) (nonspecified subtype) | MYH9 | HLA-DQA1 | FBN1 | LOC101927741 | NR3C1 | GSR | BBS9 | EPHX2 | FDX1 | PADI4

Note: If you'd like to get a target analysis report for IgA Nephropathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of IgA Nephropathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Gestational Trophoblastic Disease | Cohen Syndrome | Nanophthalmos | Osteoporosis | Vitiligo | Diabetes Insipidus, Nephrogenic | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Cardiac Sarcoidosis | Methylmalonic Aciduria And Homocystinuria, CblC Type | Tyrosine Hydroxylase Deficiency | Ischemia | Menkes Disease | Bronchiolitis | Glycogen Storage Disease Type 1b | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Centronuclear Myopathy | Thanatophoric Dysplasia Type 1 | Pierson Syndrome | Sleep Disorder | Glaucoma, Congenital | Microcephalic Primordial Dwarfism | Hypothyroidism | Rash | Turner's Syndrome | Retinal Dystrophy, Early-onset Severe | Angioedema, Acquired | Craniolenticulosutural Dysplasia | Alzheimer Disease, Late Onset | Synovitis | Pelvic Inflammatory Disease | Glioma | Autoimmune Polyendocrine Syndrome | Neurodermatitis | Transient Bullous Dermolysis Of The Newborn | Hyperuricemic Nephropathy, Familial Juvenile | Ichthyosis | Usher Syndrome Type I | Japanese Encephalitis | Spinocerebellar Ataxia Type 42 | Adenosine Deaminase Deficiency | Lattice Corneal Dystrophy Type 1 | Constipation | Microphthalmia | Atrioventricular Septal Defect | Coronary Artery Disease | Lymphoproliferative Disease, X-linked | Nephropathy | Klinefelter Syndrome | Corneal Dystrophies, Hereditary | Hepatitis, Chronic | Purpura, Thrombotic Thrombocytopenic | Hypohidrotic Ectodermal Dysplasia | Thrombocythemia, Essential | Lichen Sclerosus | Mevalonate Kinase Deficiency | Asphyxia Neonatorum | Lathosterolosis | Chronic Thromboembolic Pulmonary Hypertension | Mosaic Variegated Aneuploidy Syndrome 2 | Senior-Loken Syndrome | Clouston Hidrotic Ectodermal Dysplasia | Intestinal Tuberculosis | Adult Polyglucosan Body Disease | Hemorrhagic Disorders | Depression | Urethritis | Urofacial Syndrome | Beare-Stevenson Syndrome | Antley-Bixler Syndrome | Periodic Limb Movement Disorder | Malignant Fibrous Histiocytoma | Carcinoma, Transitional Cell | Amelogenesis Imperfecta | Stroke, Hemorrhagic | Cole-Carpenter Syndrome | Facioscapulohumeral Muscular Dystrophy | Craniopharyngioma | Cramp Fasciculation Syndrome | Saul-Wilson Syndrome | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Mycosis Fungoides | Loeys-Dietz Syndrome Type 4 | Hypospadias | Tangier Disease | Milk Allergy | Majeed Syndrome | Spasticity | Heavy Chain Disease | Hepatitis D | Williams Syndrome | Infantile Refsum Disease | Alexander Disease | Tinea | Obesity | Ameloblastoma | Juvenile Myelomonocytic Leukemia | Cranial Nerve Disease | Macular Degeneration | Psoriasis | Inflammatory Myopathy | Rubinstein-Taybi Syndrome | Sporadic Inclusion Body Myositis | Pernicious Anemia | Hereditary Xerocytosis | Heart Failure | Pancytopenia | Cholecystitis | Riboflavin Transporter Deficiency Neuronopathy | Schuurs-Hoeijmakers Syndrome | Congenital Myopathy | Calcium Pyrophosphate Deposition Disease | Giant Cell Glioblastoma | Retinitis | Hypertensive Retinopathy | Hypertension, Essential | Skin Fragility-woolly Hair Syndrome | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Waardenburg Syndrome Type 4 | IMAGe Syndrome | Focal Cortical Dysplasia Type 2 | Hepatic Steatosis | Vascular Cognitive Impairment | Chronic Kidney Disease | Frank-ter Haar Syndrome | Gigantism | Castleman Disease | Leukoencephalopathy, Progressive Multifocal | Zimmermann-Laband Syndrome | Pemphigus Vulgaris | Pregnancy, Ectopic | Charcot-Marie-Tooth Disease, Type 2A | Hashimoto Thyroiditis | Ophthalmia, Sympathetic | Myofibrillar Myopathy | Citrullinemia | Esophagitis, Eosinophilic | Acanthosis Nigricans | Low Tension Glaucoma | Reticular Dysgenesis | Frontometaphyseal Dysplasia | Neurocysticercosis | Leukemia | Microphthalmia, Syndromic 7 | Analgesia | Antenatal Bartter Syndrome Type 1 | Neovascular Glaucoma | Osteochondrosis | Spinocerebellar Ataxia Type 16 | Scleroderma, Diffuse | Cheilitis | Ehlers-Danlos Syndrome | Best Macular Dystrophy | Congenital Stationary Night Blindness | Rhabdomyosarcoma, Embryonal | Waardenburg Syndrome | Learning Disability | Beckwith-Wiedemann Syndrome | Genitopatellar Syndrome | Prader-Willi Syndrome | Pterygium | Pleurisy | Fibrosarcoma | Neuroleptic Malignant Syndrome | Epidermolysis Bullosa Simplex | Basal Ganglia Disease, Biotin-responsive | Cerebrovascular Disorders | Cardiofaciocutaneous Syndrome | Glomerulonephritis, Membranoproliferative | Coenzyme Q10 Deficiency | Usher Syndrome Type II | Autosomal Recessive Bestrophinopathy | Presbyopia | Cluster Headache | Hypermetropia | Porphyria | Kabuki Syndrome 2 | Growth Hormone Excess | Non-Langerhans Cell Histiocytosis | Dysmorphophobia | Hemosiderosis | Diastrophic Dysplasia | Heterotopic Ossification | Leukemia-lymphoma, Adult T-cell | Tyrosinemia Type 2 | Acrocallosal Syndrome | Uterine Leiomyoma | Herpes Simplex Dermatitis | Proctitis | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Holt-Oram Syndrome | Granuloma Annulare | Carbohydrate Metabolism Disorders | Spinocerebellar Ataxia Type 14 | Hereditary Multiple Exostoses | WAGR Syndrome | Chronic Lymphocytic Leukemia | Endometritis | Neuropathy | Tinea Versicolor | IgA Deficiency | Hereditary Spherocytosis | Chorea | Meningioma | Spitz Nevus | Pancreatitis | Early Infantile Epileptic Encephalopathy 4 | Lymphoma | ACTH-independent Macronodular Adrenal Hyperplasia | Neurotoxicity | Larsen Syndrome | Esophageal Adenocarcinoma | Hyperkeratosis | Bronchiectasis | VACTERL/VATER Association | Autonomic Neuropathy | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Chronic Inflammatory Demyelinating Polyneuropathy | Seminoma | Hemolytic Anemia | Chronic Granulomatous Disease, X-linked | DEND Syndrome | Erythromelalgia | Inborn Errors Of Metabolism | Intracranial Hypertension | Cutaneous Mastocytosis | Epicondylitis | Familial Hypobetalipoproteinemia | Melnick-Needles Syndrome | Transthyretin-related Amyloidosis | Congenital Hemolytic Anemia | Cancer, Lung | HELLP Syndrome | Autoimmune Autonomic Ganglionopathy | Intellectual Disability, Autosomal Dominant 5 | Methemoglobinemia | Seborrheic Dermatitis | Cerebral Cavernous Malformations | Bernard-Soulier Syndrome | Otopalatodigital Syndrome Type 2 | Jalili Syndrome | Cousin Syndrome | Vulvovaginitis | Disseminated Intravascular Coagulation | Tietze Syndrome | Trichorhinophalangeal Syndrome | Juvenile Xanthogranuloma | Aneurysm, Thoracic Aortic | Cartilage Disorders | Hereditary Hemorrhagic Telangiectasia | Cysticercosis | Hemochromatosis Type 1 | Congenital Poikiloderma | Hepatic Adenomatosis | Abetalipoproteinemia | Sotos Syndrome | Muscle Wasting | Chordoma | Dysthymia | Cancer, Brain | Hypotrichosis | Facioscapulohumeral Muscular Dystrophy Type 1 | Maternally Inherited Diabetes And Deafness | Cirrhosis | Jacobsen Syndrome | Keratocystic Odontogenic Tumor | Endophthalmitis | Batten Disease | Progressive Osseous Heteroplasia | Asthma, Nocturnal | Hyperprolactinemia | Wolfram Syndrome | Progressive External Ophthalmoplegia | Peripheral T-cell Lymphoma | Mood Disorder | Bullous Pemphigoid | Pseudohypoparathyroidism Type 1B | Wolff-Parkinson-White Syndrome | Crisponi Syndrome | Polycystic Kidney, Autosomal Recessive | Filariasis | Vaginitis | Otitis Media | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Episodic Ataxia Type 2 | Macrophagic Myofasciitis | Myoclonus-dystonia Syndrome | Raine Syndrome | Amebiasis | Vitreoretinopathy, Proliferative | B-cell Prolymphocytic Leukemia | Nager Acrofacial Dysostosis | Hereditary Folate Malabsorption | Multifocal Motor Neuropathy | Blepharoconjunctivitis | Hypertension, Renal | Benign Familial Pemphigus | Anorchia | Ectopia Lentis, Isolated, Autosomal Recessive | Double Outlet Right Ventricle | CHARGE Syndrome | Amelanotic Melanoma | Oculodentodigital Dysplasia | Polydactyly | Lipid Storage Myopathy | Delayed Sleep Phase Syndrome | Epilepsy, Generalized | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Hemangioblastoma | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Plasmacytoma | Sweet Syndrome | Olmsted Syndrome | Primary Biliary Cholangitis | Spinocerebellar Ataxia Type 17 | L-2-Hydroxyglutaric Aciduria | Monilethrix | Tuberculous Meningitis | Gnathodiaphyseal Dysplasia | Multiple Sclerosis, Secondary Progressive | Palsy, Cerebral | Yellow Fever | Osteoarthritis | Aneurysm, Abdominal Aortic | C3 Glomerulopathy | Panic Disorder | Episodic Ataxia | Eating Disorder | Schistosomiasis Mansoni | Cystinosis | Retinal Vasculitis | Polyradiculopathy | Duchenne Muscular Dystrophy | Snyder-Robinson Syndrome | Angioimmunoblastic T-cell Lymphoma | Adrenomyeloneuropathy | Cardiomyopathy, Peripartum | Adenomyosis | Pseudohypoparathyroidism Type 2 | Pitt-Hopkins Syndrome | Early Infantile Epileptic Encephalopathy 28 | Syncope | Autosomal Recessive Spastic Paraplegia Type 75 | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Orotic Aciduria | Fibrillation, Atrial | Bacterial Meningitis | Melanoma, Malignant | Chloridorrhea, Congenital | Varices | Primary Aldosteronism | Amish Infantile Epilepsy Syndrome | Epiphyseal Chondrodysplasia, Miura Type | Astrocytoma, Anaplastic | Optic Neuropathy, Anterior Ischemic | Hartsfield Syndrome | Omenn Syndrome | Hypokalemic Periodic Paralysis | Atrial Septal Defect | Osteosclerosis | Hypersomnia | Takenouchi-Kosaki Syndrome | Vogt-Koyanagi-Harada Syndrome | Renal Oncocytoma | Pulmonary Capillary Hemangiomatosis | Retinopathy Of Prematurity | Familial Male-limited Precocious Puberty | Sarcoidosis, Pulmonary | Spinocerebellar Ataxia Type 2 | Chorioretinitis | Viral Meningitis | Walker-Warburg Syndrome | Hyperparathyroidism | Farber Disease | Hemophilia | Corneal Ulcer | Osteopathia Striata With Cranial Sclerosis | Pearson Syndrome | Branchiootorenal Syndrome | Creutzfeldt-Jakob Disease | Retinal Telangiectasia | Autoimmune Hemolytic Anemia | Synpolydactyly | Lipoma | ICF Syndrome | Huntington's Disease-like 2 | Lassa Fever | Lactose Intolerance | Bipolar Disorder | Myopia | Glaucomatocyclitic Crisis | Renal Medullary Carcinoma | Frontotemporal Dementia | Schwannomatosis | Lymphangioma | H Syndrome | Pain | Nephroblastoma | Neuronal Ceroid Lipofuscinosis | Basal Cell Nevus Syndrome | Amyotrophic Lateral Sclerosis, Juvenile