Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
X-linked Acrogigantism | Depression | Carcinoma, Small Cell | Enhanced S-cone Syndrome | Congenital Adrenal Hyperplasia 1 | Anorexia Nervosa | AIDS | Waldenstrom Macroglobulinemia | Twin-to-twin Transfusion Syndrome | Spastic Paraplegia Type 7 | Primary Hyperoxaluria Type 3 | Hyperammonemia | Kabuki Syndrome | Spinocerebellar Ataxia Type 20 | Endometrial Hyperplasia | Rolandic Epilepsy | Gastroschisis | Ameloblastic Carcinoma | Empyema | Lymphangioleiomyomatosis | Alopecia | Hypersomnia | Alazami Syndrome | Hereditary Mixed Polyposis Syndrome | Esophagitis | Gynecomastia | Senior-Loken Syndrome | Chorea | Hypertension, Pulmonary | Non-bullous Congenital Ichthyosiform Erythroderma | Glycogen Storage Disease Type 5 | Dysplastic Nevus | Adrenal Insufficiency | Temporal Lobe Epilepsy | Aplastic Anemia | Brachial Plexus Neuropathy | Mevalonate Kinase Deficiency | Perry Syndrome | Fahr Disease | Guillain-Barre Syndrome | Gitelman Syndrome | Myelitis, Transverse | Lymphangiomatosis | Ureteropelvic Junction Obstruction | Alveolar Capillary Dysplasia | Acanthosis Nigricans | Pemphigus Vulgaris | Adenylosuccinate Lyase Deficiency | Osteopathia Striata With Cranial Sclerosis | Sitosterolemia | Anti-NMDA Receptor Encephalitis | Carcinoma, Squamous Cell | 3-hydroxy-3-methylglutaric Aciduria | Rickets | Osteomyelitis | Demyelinating Diseases | Chromosome 17q21.31 Deletion Syndrome | Dystrophy, Cone-rod | Juvenile Myoclonic Epilepsy | Hyperkeratosis | Gestational Trophoblastic Disease | Lymphedema-distichiasis Syndrome | Esophageal Carcinoma | Oral Lichen Planus | Retinitis | Carbohydrate Metabolism Disorders | Genee-Wiedemann Syndrome | Malignant Peripheral Nerve Sheath Tumor | Prader-Willi Syndrome | Cardiomyopathy, Restrictive | Hereditary Hemorrhagic Telangiectasia | Insulinoma | Lathosterolosis | Iron Deficiency Anemia | Leukoplakia, Oral | Neurodevelopmental Disorders | VACTERL/VATER Association | Kindler Syndrome | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Autosomal Recessive Congenital Ichthyosis | Obesity, Morbid | Smoldering Myeloma | Anovulation | Congenital Tufting Enteropathy | Glaucomatocyclitic Crisis | Ehlers-Danlos Syndrome | N-acetylglutamate Synthase Deficiency | Autism Spectrum Disorders | Tendinitis | Sialidosis | Cardiomyopathy, Hypertrophic | Migraine | Guttate Psoriasis | Oculocutaneous Albinism Type 2 | Distal Myopathy | Rothmund-Thomson Syndrome | Nijmegen Breakage Syndrome | Cryoglobulinemia | Gilbert Syndrome | Macular Corneal Dystrophy | Ectodermal Dysplasia | Spinal And Bulbar Muscular Atrophy | Tatton-Brown-Rahman Syndrome | Osteogenesis Imperfecta Type III | Bardet-Biedl Syndrome | Subcortical Band Heterotopia | Irritable Bowel Syndrome | Primary Familial Brain Calcification | Palmoplantar Keratoderma | Pneumonia, Bacterial | Nephrocalcinosis | Pemphigus | Spinocerebellar Ataxia Type 14 | Absence Epilepsy | Chanarin-Dorfman Syndrome | Multiple Sclerosis, Chronic Progressive | Polycythemia | Chitayat Syndrome | Lafora Disease | Seasonal Mood Disorder | Periodontitis | Amenorrhea | Nail Disorder, Nonsyndromic Congenital | Keratosis, Actinic | Angiosarcoma | Stargardt Disease | Auriculocondylar Syndrome | Pituitary Stalk Interruption Syndrome | Currarino Syndrome | Teratozoospermia | Pulmonary Sclerosing Hemangioma | Birt-Hogg-Dube Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Hypobetalipoproteinemias | Ovarian Sex Cord-stromal Tumor | Thrombophilia | Heroin Dependence | Chromosome 8q21.11 Deletion Syndrome | Glioblastoma | Phenylketonuria | Alstrom Syndrome | Adenomatoid Tumor | Leukocyte Adhesion Deficiency | Neurocutaneous Syndromes | Narcolepsy | Ollier Disease | Myopathy | Craniometaphyseal Dysplasia | Central Pain Syndrome | Congenital Disorders Of Glycosylation Type II | Congenital Nephrotic Syndrome | Amblyopia | Phosphoglycerate Dehydrogenase Deficiency | Diabetes Insipidus, Neurogenic | Erythromelalgia | Cerebrotendinous Xanthomatosis | Johanson-Blizzard Syndrome | Spermatocele | Gerodermia Osteodysplastica | Multicystic Renal Dysplasia | Charcot-Marie-Tooth Disease Axonal Type 2N | Inborn Errors Of Metabolism | Leukoencephalopathy, Progressive Multifocal | Membranous Nephropathy | Cystitis, Interstitial | Renal Medullary Carcinoma | Campomelic Dysplasia | Cri-du-chat Syndrome | Esophageal Motility Disorders | Sensorineural Hearing Loss | Cystinuria | Adenomyosis | Aldosteronism | Transcobalamin Deficiency | Dowling-Degos Disease | Pierpont Syndrome | Tenosynovial Giant Cell Tumor | Scoliosis | Corneal Dystrophies, Hereditary | Pericarditis | Seborrheic Dermatitis | Headache | Joubert Syndrome | Short-chain Acyl-CoA Dehydrogenase Deficiency | Myositis, Focal | Nephrotic Syndrome | Nutrition Disorders | Pemphigoid | Hyperuricemia | Huntington's Disease | Oculocutaneous Albinism | Congenital Fiber-type Disproportion Myopathy | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Insulin Resistance | Ectopia Lentis, Isolated, Autosomal Recessive | Stevens-Johnson Syndrome | Acrocallosal Syndrome | Alpha-mannosidosis | Chromosome 5q Deletion Syndrome | Goiter, Nodular | Spinal Muscular Atrophy Type 3 | Rhizomelic Chondrodysplasia Punctata | Liddle Syndrome | Distal Spinal Muscular Atrophy | Primary Sclerosing Cholangitis | Bulimia Nervosa | Coma | Dermatomyositis | Allergic Contact Dermatitis | Fetal Alcohol Syndrome | Progressive Familial Intrahepatic Cholestasis Type 3 | Acute Motor Axonal Neuropathy | Tyrosinemia Type 2 | Carbamoyl Phosphate Synthetase I Deficiency | Huntington's Disease-like 2 | Papilloma | Chronic Leukemia | Hypertriglyceridemia | Hypertension, Renal | Lysosomal Acid Lipase Deficiency | Trichothiodystrophy | Arrhythmogenic Right Ventricular Cardiomyopathy | Acute Lymphocytic Leukemia | Glioblastoma Multiforme | Protein S Deficiency | Gastritis, Atrophic | Cryptorchidism | Pathological Gambling | Alcoholism | Congenital Afibrinogenemia | Hyperparathyroidism, Primary | Pachyonychia Congenita | Palsy, Cerebral | Hyper IgE Syndrome | Agranulocytosis | Otosclerosis | Preaxial Polydactyly | Encephalopathy | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Infantile Refsum Disease | Zimmermann-Laband Syndrome | Transthyretin-related Amyloidosis | Keratocystic Odontogenic Tumor | Nemaline Myopathy 10 | Pernicious Anemia | Erythema Multiforme | Periventricular Leukomalacia | Hereditary Folate Malabsorption | Traboulsi Syndrome | Adenoma, Pleomorphic | Moyamoya Disease | Tyrosine Hydroxylase Deficiency | Acrodermatitis | Tuberculosis | Antley-Bixler Syndrome | Neonatal Progeroid Syndrome | Splenomegaly | Sickle Cell Disease | Primary Hyperoxaluria Type 1 | Progressive Myoclonic Epilepsy | Multiple Sclerosis, Relapsing-remitting | Postpoliomyelitis Syndrome | Uveitis | Papulopustular Rosacea | Familial Glucocorticoid Deficiency | Nasodigitoacoustic Syndrome | Paraganglioma | Carcinoma In Situ | Hartsfield Syndrome | Panuveitis | Leukocyte Adhesion Deficiency Type 1 | Charcot-Marie-Tooth Disease Type 2D | Stiff-man Syndrome | Hepatopulmonary Syndrome | Speech Disorders | Carcinoma, Merkel Cell | Retinoschisis | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Charcot-Marie-Tooth Disease Type 4B1 | Open-angle Glaucoma | Hereditary Coproporphyria | Galloway-Mowat Syndrome | Neurofibromatosis Type 1 | Intellectual Disability, Autosomal Dominant 5 | Encephalopathy, Hepatic | Myosin Storage Myopathy | Epidermodysplasia Verruciformis | Fibrosarcoma | Long QT Syndrome Type 2 | Colitis | Intracranial Hypertension | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Carcinoid Tumor | Anencephaly | Limb Girdle Muscular Dystrophy | Keratoconus | Rubeosis Iridis | Vestibular Disease | Low Tension Glaucoma | Neurodermatitis | Hydrops Fetalis | Malaria | Acrodermatitis Enteropathica | Familial Episodic Pain Syndrome | Charcot-Marie-Tooth Disease Type 2E | Klinefelter Syndrome | Wolman Disease | Coronary Artery Disease | Hyperinsulinism-hyperammonemia Syndrome | Persistent Mullerian Duct Syndrome | Hermansky-Pudlak Syndrome | Chloridorrhea, Congenital | Keratoconjunctivitis | Veno-occlusive Disease | Aplasia Cutis Congenita | Otopalatodigital Syndrome Type 2 | Macrophage Activation Syndrome | Omenn Syndrome | Diabetic Macular Edema | Lamellar Ichthyosis | Autonomic Nervous System Disorders | Lung Diseases | Mucolipidosis Type III | Infantile Spasm | Trichorhinophalangeal Syndrome | Astigmatism | Progressive Encephalopathy-optic Atrophy Syndrome | Alopecia Areata | Leber Hereditary Optic Neuropathy | Holt-Oram Syndrome | Hereditary Neuropathy With Liability To Pressure Palsies | Sporadic Hemiplegic Migraine | Carotid Artery Disease | Metabolic Diseases | Heart Failure | Sclerosing Cholangitis | Rhabdoid Tumor | Alagille Syndrome | Rhabdomyosarcoma, Alveolar | Constipation | Nestor-Guillermo Progeria Syndrome | Dystonia Musculorum Deformans | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Peritonitis | Trimethylaminuria | Specific Granule Deficiency | Tricho-hepato-enteric Syndrome | Cannabis Abuse | Aspergillosis | Craniolenticulosutural Dysplasia | Niemann-Pick Disease, Type A | Placenta Previa | Whipple's Disease | Anorectal Fistula | Early Infantile Epileptic Encephalopathy 13 | Neuropathy | Weill-Marchesani Syndrome | Carey-Fineman-Ziter Syndrome | Primary Biliary Cholangitis | Communication Disorders | Abetalipoproteinemia | Primrose Syndrome | Multiple Sulfatase Deficiency | Amelogenesis Imperfecta | Chronic Granulomatous Disease, X-linked | Dermatofibrosarcoma | Coronary Restenosis | Gerstmann-Straussler-Scheinker Syndrome | Pseudohypoparathyroidism Type 1A | Renal-hepatic-pancreatic Dysplasia | Optic Nerve Diseases | Dysequilibrium Syndrome | Chorioretinitis | Gastroenteritis, Eosinophilic | Brugada Syndrome 1 | SAPHO Syndrome | Motion Sickness | Anorchia | Transient Bullous Dermolysis Of The Newborn | Usher Syndrome Type IIC | Cryopyrin-associated Periodic Syndromes | Aicardi-Goutieres Syndrome | Schizophrenia | Multifocal Motor Neuropathy | Infantile Nephropathic Cystinosis | Varices | Diabetic Encephalopathy | Marinesco-Sjogren Syndrome | Intestinal Pseudo-obstruction | Myoclonic Atonic Epilepsy | Leber Congenital Amaurosis | Scleroderma, Diffuse | Sarcoma | Facioscapulohumeral Muscular Dystrophy Type 1 | Glycogen Storage Disease Type 0 | Discoid Lupus Erythematosus | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Hyperoxaluria | Hyperprolactinemia | Spondyloperipheral Dysplasia