Gaucher Disease

About the Disease
Gaucher's Disease, also known as gaucher disease, is related to gaucher disease, type ii and gaucher disease, type iii, and has symptoms including apnea, muscle rigidity and muscle spasticity. An important gene associated with Gaucher's Disease is GBA1 (Glucosylceramidase Beta 1), and among its related pathways/superpathways are Metabolism and Sphingolipid metabolism. The drugs Sofosbuvir and Ledipasvir have been mentioned in the context of this disorder. Affiliated tissues include spleen, liver and bone marrow, and related phenotypes are splenomegaly and hepatomegaly

Common Targets
CPVL | Histone deacetylase (nonspecified subtype) | Glucosidase (nonspecified subtype) | LYZ | GBA1 | MPHOSPH8 | Glycogen phosphorylase (nonspecified subtype) | LRRK2 | ASAH1 | UGCG | CHIT1 | Chaperone (nonspecified subtype) | CMYA5 | HLA-B | SLC5A4 | GUSB | PSAP | ZNF737 | HLA-DRB1 | HMMR | HLA-A | USH2A | ERN1 | Heat shock protein 70 (nonspecified subtype) | CACNA1A | PCDHB8 | GBA2 | GLB1 | MEST | DNAJC5 | GAA | NPC1 | GALC | TEAD3 | alpha-Mannosidase (nonspecified subtype) | GLA

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