Pleomorphic Xanthoastrocytoma
Pleomorphic Xanthoastrocytoma
About the Disease
Pleomorphic Xanthoastrocytoma, also known as pxa, is related to glioma susceptibility 1 and malignant astrocytoma, and has symptoms including seizures An important gene associated with Pleomorphic Xanthoastrocytoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are "Cell Cycle, Mitotic" and Prolactin Signaling. The drugs Dabrafenib and Trametinib have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and temporal lobe, and related phenotypes are neoplasm and normal
Common Targets
RPTOR | NOTCH3 | FANCD2 | ETV4 | CSF1R | RARA | RAD52 | CHEK1 | NUP93 | CDK4 | G673 | CDKN2B | TRRAP | PPP2R1A | G1029 | G4851 | PDGFRB | ARID2 | NOTCH4 | ROS1 | XPO1 | TBX3 | FLT4 | G7157 | GATA2 | G999 | SMARCA4 | MRE11 | GSK3B | MEN1 | FANCI | RAF1 | G2033 | FGFR4 | FGF19 | FGF23 | CCNE1 | G4233 | DOT1L | VCP | PBRM1 | NF1 | FANCA | RUNX1 | MGMT | LRP1B | NOTCH2 | PARP4 | ARID1A | G2146 | G3845 | MSH6 | PIK3CG | RNF43 | G472 | KDM5A | FANCM | MED12
![疾病靶点研报](../img/disease-target-analysis-report.jpg)
Note: If you'd like to get a target analysis report for Pleomorphic Xanthoastrocytoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Pleomorphic Xanthoastrocytoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.
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