Congestive Heart Failure

About the Disease
Congestive Heart Failure, also known as congestive heart disease, is related to cardiomyopathy, dilated, 1e and orthostatic intolerance, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Congestive Heart Failure is CDKN2B-AS1 (CDKN2B Antisense RNA 1), and among its related pathways/superpathways are Cardiac conduction and "Antiarrhythmic Pathway, Pharmacodynamics". The drugs Salbutamol and Thalidomide have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Lateral Plate Mesoderm, and related phenotypes are muscle and homeostasis/metabolism

Common Targets
CBR3 | SLC28A3 | CYP2D6 | CNR1 | Alpha-2 Adrenergic receptors (nonspecified subtype) | KCND3 | CYP17A1 | AGT | HSPB7 | IKZF1 | CYP7A1 | TRPV4 | T-Type Calcium Channel | Endothelin-Converting Enzymes (ECE) (nonspecified subtype) | GABA(A) receptor | AVPR1B | ACHE | ADORA1 | APLNR | Thyroid hormone receptor (nonspecified subtype) | IP6K2 | ABCB4 | HTR4 | CACNA1G | RAC2 | CYP8B1 | G4318 | TGFBR1 | F2 | DBH | Sodium channel (nonspecified subtype) | XDH | SLC9A3 | AVPR2 | PTPN1 | NOS3 | HPGD | Guanylate cyclase (nonspecified subtype) | OXT | FPGT-TNNI3K | EDNRB | ADCY2 | NCF4 | CES1 | VIPR1 | TNNI3K | MMP2 | UTS2R | PDE5A | UGT1A6 | RYR2 | Na+/K+-ATPase (nonspecified subtype) | KCNA5 | ADRB1 | MME | DRD1 | ADCY6 | ADCY5 | NPY5R | beta-Adrenoceptor (nonspecified subtype) | CYP11B1 | F5 | CALCRL | CHIA | AGTR1 | FMO2 | MMP13 | JAK2 | GHR | L-Type calcium channel (nonspecified subtype) | IKZF3 | G7124 | JAK1 | NLRP3 Inflammasome | Vasopressin Receptor (nonspecified subtype) | CRBN | G114548 | Ikzf1 | Adenosine receptor (nonspecified subtype) | SLC10A2 | CYP19A1 | F11 | AGTR2 | GUCY2C | KLKB1 | MMP8 | ABCC1 | ECE1 | GLP1R | NPR1 | G673 | SLC2A9 | OXTR | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | CYP11B2 | Rho kinase (ROCK) (nonspecified subtype) | CYP27B1 | REN | SIRT3 | AMP-activated protein kinase (AMPK) | CRHR2 | HDAC6 | HIF1A | CMA1 | EDNRA | ACE | PDE3A | IP6K1 | CYBA | CAT | ECE2 | AVPR1A | SLC12A1 | LDLR | Interleukin 17 (nonspecified subtype) | FAP | IP6K3 | CACNA1H | DRD2 | PDE4B | GPR35 | NR3C2 | TYK2 | PPARA | NPR3 | SLC12A2 | L-type voltage-dependent calcium channel complex

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