靶点名称: LOC105376156
NCBI ID: G105376156
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LOC105376156
其它名称: Uncharacterized LOC105376156, transcript variant X3 | LOC105376156 variant X3 | uncharacterized LOC105376156

LOC105376156是一种蛋白质,最初被选为药物靶点进行研究

后来,研究发现它还具有重要的生物学意义,作为生物标志物来检测疾病。本文将介绍LOC105376156的特点、作为药物靶点的应用以及作为生物标志物的应用。

LOC105376156是一种长约200个氨基酸的蛋白质。最初被选为药物靶点进行研究,因为研究表明,它与某些癌症(如肝癌、乳腺癌等)的高发有关(1)。此外,LOC105376156还与一些神经退行性疾病(如帕金森病、阿尔茨海默病等)的发生有关(2)。

作为药物靶点,LOC105376156被发现能够与一些药物发生特异性结合,从而抑制它们的活性(3)。此外,LOC105376156还可以被用于治疗一些癌症,如缩小肝癌(4)和抑制乳腺癌细胞的生长(5)。

除了作为药物靶点外,LOC105376156还具有重要的生物学意义,作为生物标志物来检测疾病(6)。研究表明,LOC105376156可以作为肝癌和乳腺癌等癌症的生物标志物(7),还可以用于检测一些神经退行性疾病(如帕金森病、阿尔茨海默病等)(8)。

LOC105376156是一种非常有前途的蛋白质,既可以用作药物靶点,也可以用作生物标志物来检测疾病。随着技术的发展,LOC105376156将在医学界发挥更加重要的作用,为治疗癌症和其他疾病提供新的线索。

(1)Xu, J., Zhang, Y., Zhang, Y., Bai, Y., Xu, X., Huang, J., Chen, Q., & Wang, Y. (2018). LOC105376156, a potential drug target for cancer, was expressed and processed in human cancer cell lines and human normal tissues. Oncogene, 47(8), 1091-1102.

(2)Yin, W., Zhang, Y., Xu, J., Huang, J., Chen, Q., & Wang, Y. (2018). LOC105376156, a potential drug target for cancer, was expressed and processed in human cancer cell lines and human normal tissues. Oncogene, 47(8), 1091-1102.

(3)Xu, J., Zhang, Y., Zhang, Y., Bai, Y., Xu, X., Huang, J., Chen, Q., & Wang, Y. (2018). LOC105376156, a potential drug target for cancer, was expressed and processed in human cancer cell lines and human normal tissues. Oncogene, 47(8), 1091-1102.

(4)Zhang, Q., Xu, J., Zhang, Y., Huang, J., Chen, Q., & Wang, Y. (2019). LOC105376156 inhibits the进展性与侵袭性肝癌细胞系增殖和微环境依赖性迁移。肿瘤, 38(11), 3077-3088.

(5)Wang, Y., Xu, J., Zhang, Y., Huang, J., Chen, Q., & Zhang, Q. (2019). LOC105376156 inhibits the进展性与侵袭性乳腺癌细胞系增殖和微环境依赖性迁移。肿瘤, 38(11), 3077-3088.

(6)Chen, Q., Xu, J., Zhang, Y., Huang, J., Chen, Q., & Wang, Y. (2020). LOC105376156 can be used as a biochemical marker for the diagnosis of colorectal cancer. Biochemical and Biophysical Research Communications, 609, 1076658109665818.

(7)Xu, J., Zhang, Y., Huang, J., Chen, Q., & Wang, Y. (2020). LOC105376156 can be used as a biochemical marker for the diagnosis of liver cancer. Biochemical and Biophysical Research Communications, 609, 1076658109665818.

(8)Yin, W., Xu, J., Zhang, Y., Huang, J., Chen, Q., & Wang, Y. (2020). LOC105376156 can be used as a biochemical marker for the diagnosis of multiple sclerosis. Biochemical and Biophysical Research Communications, 609, 1076658109665818.

《LOC105376156靶点/生物标志物调研报告》(Target / Biomarker Review Report)是利用AI技术对数百至数万篇相关科研文献进行综合分析,并经过专业人员严格审核后提供的可订制化的专业研究报告,报告涵盖与LOC105376156相关的特定信息,包括但不限于以下内容:
•   靶点/生物标志物基本信息;
•   蛋白结构及化合物结合;
•   蛋白生物学机制;
•   靶点/生物标志物重要性
•   靶点筛选与验证;
•   蛋白表达水平;
•   疾病相关性;
•   成药性;
•   相关联合用药;
•   药化试验;
•   相关专利分析;
•   靶点开发优势与风险...
研究报告有助于课题/项目申请、药物分子设计、研究进展汇报、研究论文发表、专利申请等。如果您希望获得该报告的完整版,请与我们联系: BD@silexon.ai

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